Clostridium difficile: moving beyond antimicrobial therapy
نویسندگان
چکیده
منابع مشابه
Clostridium difficile: moving beyond antimicrobial therapy
DM: Treatment with monoclonal antibodies against Clostridium diffi cile toxins.
متن کاملAntimicrobial therapy of Clostridium difficile-associated diarrhea.
Clostridium difficile-associated diarrhea (CDAD) is the most common etiologically-defined cause of hospital-acquired diarrhea. Caused by the toxins of certain strains of C difficile, CDAD represents a growing concern, with epidemic outbreaks in some hospitals where very aggressive and difficult-to-treat strains have recently been found. Incidence of CDAD varies ordinarily between 1 to 10 in eve...
متن کاملClostridium difficile--beyond antibiotics.
In this decade, the prevention and control of Clostridium difficile infection in health care settings has become a global public health challenge. Infection rates have increased dramatically, and several large outbreaks associated with toxinotype III BI/NAP1/027 strains have been described.1 One of the major incongruities in the management of C. difficile infection is that antibiotics are the m...
متن کاملClostridium difficile--a moving target
Clostridium difficile has been recognized as a pathogen in humans for over 40 years, but in the past decade the incidence has increased and, more importantly, the clinical presentation and consequences have become more serious, with increased morbidity and mortality. The emergence of a new, more pathogenic strain, BI/NAP1/027, has driven these shifts. Treatment of this disease has been with two...
متن کاملAntimicrobial susceptibilities of Clostridium difficile.
The antimicrobial susceptibilities of 78 strains of Clostridium difficile isolated from patients with and without gastrointestinal symptoms were determined and compared. Strains from patients with symptoms were more likely to show resistance to antibiotics. The antimicrobial susceptibilities of toxigenic and non-toxigenic strains were found to be similar.
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ژورنال
عنوان ژورنال: Critical Care
سال: 2010
ISSN: 1364-8535
DOI: 10.1186/cc9249